Research of The Ison Method


There have been many studies on the effects of music on patients over the years. TheraSound has been part of many of these studies. However, the clinical validation of TheraSound’s effectiveness by the National Institutes of Health is the best and the most comprehensive.

At TheraSound we have always tried to create the most effective therapeutic music for our clients and their patients.  Our music was created to produce specific physiological and psychological effects on the listener.

The NIH study is important because it validates the fact that music— when specifically designed to do so, can indeed, drop pulse, reduce blood pressure, create the relaxation response and significantly reduce the levels of a number of symptoms in a wide variety of patients.

What follows is a summary by the author of the study, Dr. George Patrick, the Chief of Rehabilitation Therapy at the NIH:

Patrick, G:  The Effects of Vibroacoustic Music on Symptom Reduction.  
IEEE Engineering in Medicine and Biology
, (March-April): 97-100, 1999.



National Institute of Health Study

This is the complete National Institute of Health study  mentioned on this page.



The Use of Acoustic Therapy
in Pain Management

An Interview with David Ison published in the AMERICAN ACADEMY OF PAIN MANAGEMENT



The results of a program evaluation of anxiolytic music (“Balance” and the “Musical body Program” from Therasound) on N=272 consecutive patients at the National Institutes of Health Clinical Center with varying diagnoses were described.  The most frequently self-reported symptoms were rated on a visual analog scale (VAS):  tension, fatigue, pain, headache, depression, and nausea.  Together, these six symptoms comprised 92% of all symptoms reported.

An aggregation of all symptom data showed an average participant pre (VAS) rating of 67.20 (of 100) and a post rating of 31.55— an overall 53% reduction in symptoms for a single session. 

A one sample t-test (pre-post) was performed on each of the six symptoms and showed statistically significant differences for each at the P<.0001 level.  The Holmes test for concurrence was applied to the data indicating that these symptoms appear to be similar, lending support to the conclusion that these six symptoms were part of a larger phenomenon, likely to be stress.

Another inquiry, part of this article, was the Poppen relaxation scale (7 points anchored by a brief state of relaxation descriptions).  The Poppen results showed that relaxation and symptom reduction were highly correlated.

This is the largest (N=272) number of patients of any of anxiolytic music studies in the literature reviewed from 1992 to 2004.

CONCLUSION: The study demonstrates that a twenty minute session using TheraSound’s music will create the relaxation response as well as significantly reduce a number of the symptoms associated with stress and anxiety.